Question by Pamela Boss: What are the 38 drugs that can cause drug-induced lupus?
I just heard that someone can have drug-induced lupus.
My mother-in-law has lupus and is on a multitude of medications (for God knows what; since before diagnosed with lupus) so this issue has peaked my interest.
From doing a search, I could only find the top three medications, but I was hoping someone could tell me the 38 drugs that can cause lupus.
Answer by femmina matta
http://www.lupus.org/webmodules/webarticlesnet/templates/new_aboutindividualized.aspx?articleid=377&zoneid=18 http://en.wikipedia.org/wiki/Drug-induced_lupus_erythematosus * Alferon N
* Carbamazepine (Tegretol)
* Hydralazine (Apresoline)
* Inerferon Alfa
* Intron A
* Isoniazid (INH)
* Methyldopa (Aldornet)
* Phenytoin (Dilantin)
* Procainamide (Procan, Pronestyle)
* Quinidine (Quinaglute)
* Some anti-seizure medications
Read more at http://www.wrongdiagnosis.com/l/lupus/medic.htm?ktrack=kcplink Although as many as 100 drugs have been reported to cause DRL, most cases are caused by the following 4 drugs: procainamide (Pronestyl), hydralazine (Apresoline), minocycline, and quinidine (Quinaglute). With these 4 drugs, the risk of developing DRL after 2 years of drug use is 5-20 percent. With the other drugs reported to cause DRL, the risk is less than 1 percent.
Drugs with a definite association to DRL include: chlorpromazine (Thorazine), hydralazine, isoniazid (used for tuberculosis), minocycline, methyldopa, and the heart medications procainamide and quinidine.
Drugs reported to have a possible association with DRL include: the beta-blockers propranolol, metoprolol, and atenolol; captopril; the anticonvulsants carbamazepine (Tegretol), primidone (Mysoline), ethosuximide (Zarontin), valproic acid (Depakene, Depakote), trimethadione (Tridone), and phenytoin (Dilantin); hydralazines; interleukins; interferons; levodopa, tumor necrosis factor (TNF), tiotropium bromide inhaler, ophthalmic timolol, lithium; the anti-thyroid drugs methimazole and propylthiouracil (PTU); the chelating agent penicillamine; the antibiotics nitrofurantoin, sulfasalazine, and sulfonamides.
Drugs reported to have an unlikely or very low association with DRL include: allopurinol (used for gout), chlorthalidone and hydrochlorothiazide (diuretics), gold salts, griseofulvin, methylsergide, oral contraceptives, lovastatin, minoxidil, perphenazine, penicillin, phenylbutazone, reserpine, streptomycin, and tetracyclines. http://www.lupusalliance.org/content.asp?id=312
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